Contrary to the last International Human Genome Editing Symposium, the focus was Somatic Human Gene Editing (SHGE), wherein the non-reproductive cells of adults/children were utilized to explore cures for diseases. This approach makes changes in the patient’s DNA without causing those changes to be inherited by future offspring. In gene editing, there is always a possibility of […]

It is 2022, and even with the explosion of medical research over the last decade using CRISPR gene editing, the unwanted and off-target mutations caused by the game-changing tool have not been controlled. Furthermore, studies consistently find that these mutations are directly inherited by any offspring produced. Indeed, CRISPR has facilitated great strides in curing […]

In a ground-breaking first, researchers and surgeons at the University of Maryland Medical Center have successfully transplanted a gene-edited pig heart into a dying man. For the heart to not be rejected once transplanted, 10 separate genes were deleted or added using CRISPR, earning the donor animal the nickname of a “10 gene pig”. Over […]

NCER Comments:  Sickle Cell Anemia is a heritable disease that 1 in every 13 Black or African American babies possess when born. Red blood cells are abnormally shaped, so are unable to carry oxygen needed for all tissues and organs to survive. The average lifespan is only 40 years, but a new development using the CRISPR […]

NCER Comments: The vast majority of adults are taking a daily Statin to manage their “bad” LDL and Triglyceride Cholesterol count, and many experience muscle pain as well as other adverse side effects. Using CRISPR gene editing, two companies, Verve and Beam Therapeutics, are intensely working on an ethical solution to high cholesterol which causes […]

NCER Comments: Diabetes Mellitus (DM) affects more than 100 million adults in the US; that’s just under 10% of the population. Diabetes is associated with a 2x increase of death due to cardiovascular disease; and on average, patients with diabetes lose 6 years of their lifespan compared to those who do not. Additionally, DM is […]

MIT Technology Review The Chinese scientist and two associates were sentenced after a secret trial. by Antonio Regalado Dec 30, 2019   The Chinese scientist who created the world’s first gene-edited children has been sentenced to three years in prison by a Chinese court. He Jiankui, a biophysicist trained at Rice University and Stanford, shocked the […]

NCER Notes: Research has shown that the CRISPR gene editing tool (which cuts out and replaces diseased DNA) holds great potential for healing disease, but currently poses a significant risk to humans due to frequent unintended mistakes, or “off-target” mutations in DNA. A solution is being pursued, but in the meantime, a new kind of […]

NCER Notes: With more than 36 M HIV infected people worldwide, and over 1 M living in the U.S., a cure for the disease is fervently sought. Researchers at our own UNMC in Omaha, Ne. believe they have found that cure! Mice were injected with human stem cells from cord blood in order to create […]

NCER Notes: As an alarming example of how the gene editing of embryos can be dangerous, the first gene edited babies born in China last year now have a high probability of a significantly shorter lifespan due to unexpected consequences of the editing. Because of this outcome, the World Health Organization has asked all countries […]