NCER Open Letter to FDA Committee Regarding Gene Editing

Attn: Michael Berrios

The Committee on Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases


Dear Committee Members:

There are at least five reasons why the Board of Directors of the Nebraska Coalition for Ethical Research recommends that the FDA deny licensure for the use of mitochondrial techniques in U.S. fertility clinics or research laboratories.


  • The pronuclear transfer technique of mitochondrial replacement (MR) involves the