Sheffield Medics Help Paralysed Patients Walk Again

The Star  Jan 19, 2016

Paralysed multiple sclerosis sufferers are walking again thanks to life-changing treatment in Sheffield.

A trial at the Royal Hallamshire Hospital has seen 20 patients receive bone marrow transplants using their own stem cells in a bid to ‘re-boot’ their immune systems, which has helped some people walk again.

The trial is also being run in the US, Sweden and Brazil.

Professor Basil Sharrack, from the Royal Hallamshire Hospital, said: “To …

International Gene Editing Conference Declines to Ban Eventual Use in Humans

LA Times Dec 3, 2015  Melissa Healy

An international conference on gene editing on Thursday left the door open to future use, in humans, of new techniques that alter an organism’s genetic architecture in ways that carry forward to future generations.

With questions of safety, need and ethics still unanswered, the U.S. National Academies of Sciences, Engineering and Medicine; the United Kingdom’s Royal Society; and the Chinese Academy of Science agreed that “it would be …

Gene Editing—A Revolution From Stem to Stern

The Lancet  Dec 15, 2015  Rebecca Cooney, Editor

Gene editing has swiftly become one of the most promising—and controversial—breakthroughs in genetic engineering.

With the entrance of CRISPR (clustered regularly interspaced short palindromic repeats), a technique using  the Cas9 enzyme to cut strands of the genome at precisely targeted locations to insert, replace, or remove DNA, the manipulation of the genetic basis of human disease has once again come to the fore.

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Much of the excitement …

Stem Cell Therapy Research Yields HUGE Results In Multiple Sclerosis

MSUnites.com Nov 5, 2015

Overview:

A new stem cell treatment has sent most of the MS patients who tried it into remission, halting the progression of the disease even several years afterwards.

In a recent clinical study at the COloroda Blood Cancer Institute 24 patients with relapsing remitting multiple sclerosis (RRMS) underwent a three month procedure destroying their immune systems and then had their immune systems restarted using stem cell therapy.

The Study:

The clinical

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Is the Great Stem Cell Debate Over?

BioEdge  Michael Cook Oct 31, 2015

sn-stemcells

It’s a sign of the times.

Ten years ago, the single most controversial issue in bioethics was probably the use of human embryonic stem cells. Since these can only be obtained by destroying human embryos, nearly every Western legislature had noisy and bitter debates. But all that died away soon after Japanese researcher Shinya Yamanaka developed induced pluripotent stem cells, which apparently have all the potential of embryonic cells …

Scientists Convert Skin Cells into Placenta-Generating Cells

Science Daily  Hebrew University of  Jersusalem  Oct 14, 2015

Regenerative medicine is a new and expanding area that aims to replace lost or damaged cells, tissues or organs in the human body through cellular transplantation. Embryonic stem cells (ESCs) are pluripotent cells that are capable of long-term growth, self-renewal, and can give rise to every cell, tissue and organ in the fetus’s body. Thus, ESCs hold great promise for cell therapy as a source of …

UN Panel Calls for Moratorium on Editing Human Genome

Michael Cook  BioEdge  Oct 8, 2015

10-05-unesco-dna

Warning that rapid advances in genetics make “designer babies” an increasing possibility, a United Nations panel today called for a moratorium on “editing” the human genome, pending wider public debate lest changes in DNA be transmitted to future generations or foster eugenics.

While acknowledging the therapeutic value of genetic interventions, the panel stressed that the process raises serious concerns, especially if the editing of the human genome should be …

Kidney Disease

Harvard Stem Cell Institute

The Harvard Stem Cell Institute is developing new therapies to repair kidney damage, reducing the need for dialysis and transplantation.

Diabetes is a corrosive illness. The imbalance of blood sugar causes small changes in the body that slowly lead to blurry vision, skin rashes, and damaged nerves. In serious cases, diabetes wears away the path of blood to the kidneys, causing eventual organ failure. In fact, half of all kidney failures …

UI Health Validates Cure for Sickle Cell in Adults

UIC News Center Sept 16, 2015  Sharon Parmet

Physicians at the University of Illinois Hospital & Health Sciences System have cured 12 adult patients of sickle cell disease using a unique procedure for stem cell transplantation from healthy, tissue-matched siblings.

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Ieshea Thomas was the first adult to be cured of sickle cell anemia by chemotherapy-free treatment at UI Health.

The transplants were the first to be performed outside of the National Institutes of Health campus