Restoring Sight: CRISPR Could Reprogram Cells to Treat Retinitis pigmentosa

Genetic Literacy Project 4/28/17 University of California San Diego

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.

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Retinitis pigmentosa (RP) is a group of inherited vision disorders caused by numerous mutations in more than 60 …

China Unveils Gene Technology to Create Superhumans with Hyper-Muscular Test-tube Dogs

Express.co.uk  by Rebecca Flood July 18, 2017

Armies of super-soldiers were a step closer to reality today after China announced it was genetically engineering hyper-muscular super-dogs.

The dogs, which are test tube bred in a lab, have twice the muscle mass of their natural counterparts and are considerably stronger and faster.

The canine genome has been especially difficult to engineer and replicate – but its close similarity to the human genome means it has long

First Human Embryos Edited in the U.S.

Rewriting Life  by Steve Connor  July 26, 2017

 

A still from a video shows gene-editing chemicals being injected into a human egg at the moment of fertilization. Scientists used the technique to correct DNA errors present in the father’s sperm.
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The first known attempt at creating genetically modified human embryos in the United States has been carried out by a team of researchers in Portland, Oregon, MIT Technology Review has learned.

The effort,

Turning Skin Cells into Blood Vessel Cells While Keeping Them Young

Science Daily  April 6, 2017

This is a mouse heart section showing human progenitor cells that formed functional human blood vessels. Purple color signifies human blood vessels, red staining signifies the blood vessels of the mouse that received the human cell implants. Credit: Jalees Rehman

Researchers from the University of Illinois at Chicago have identified a molecular switch that converts skin cells into cells that make up blood vessels, which could ultimately be used to

This Fluid-Filled Bag Lets Lambs Develop Outside the Womb. Humans Are Next.

Futurism.com  Jolene Creighton  April 26, 2017

Physicians at the Children’s Hospital of Philadelphia worked with 23 week-old lambs to in order test a synthetic device that imitates a woman’s uterus, hoping to limit mortality and disease in premature children that are born before 37 weeks

Creating an artificial womb would be a feat of monumental proportions, as premature birth is the leading cause of death for newborns. And this week, Philadelphia physicians made significant strides

Unproven Stem Cell ‘Therapy’ Blinds Three Patients at Florida Clinic

Science Daily  March 15, 2017  Stanford University Medical Center

Jeffrey Goldberg and his colleagues examined the cases of three women who were blinded after undergoing an unproven stem cell treatment for macular degeneration.
Credit: Norbert von der Groeben
Three people with macular degeneration were blinded after undergoing an unproven stem cell treatment that was touted as a clinical trial in 2015 at a clinic in Florida. Within a week following the treatment, the patients experienced

Is the 14-day Limit on Growing Embryos Out of Date?

BioEdge April 3, 2017  Michael Cook

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Both in the US and UK, growing human embryos more than 14 days in a laboratory is banned. Recent developments suggest that it may be possible to grow them for longer and a number of scientists are lobbying to extend the limit. They contend that the limit is out-of-date and too restrictive.

But what if they could create embryo-like structures without creating complete embryos? This possibility is completely unregulated.…

Dutch Health Council Authorizes the Creation of Human Embryos for Research

BioEdge  April 3, 2017  Xavier Symons

The Dutch Health Council (Gezondheidsraad) has recommended that scientists be allowed to create embryos specifically for research purposes, in a move that will pave the way for embryo gene editing research in the Netherlands.

In a report submitted Tuesday to Minister for Health Edith Schippers, the Health Council recommended that the government abandon the current regulations that only allow research scientists to use embryos left over from procedures such …

A Yellow Light for Embryo Editing

Jocelyn Kaiser Science Feb 17,2017

Editing the DNA of a human embryo to prevent a disease in a baby could be ethically allowable one day—but only in rare circumstances and with safeguards in place, says a widely anticipated report released today.

The report from an international committee convened by the U.S. National Academy of Sciences (NAS) and the National Academy of Medicine in Washington, D.C., concludes that such a clinical trial “might be permitted, but …

Human Adult Stem Cells (iPS) Have Been Found to be Most Clinically Useful Human Cells for Therapeutic Purposes

Justo Aznar Bioethics Observatory Catholic University of Valencia

Human adult stem cells (iPS) have been found to be most clinically useful human cells for therapeutic purposes.

Pluripotent cells (PCs) are defined as those from which cells of different tissue types can be obtained. These can be obtained either from preimplantation human embryonic cells, in which case pluripotent embryonic stem cells are obtained, or from somatic (adult) cells that can be reprogrammed to a state of …