Science Daily Jan 6, 2016 Gladstone Institute
Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF) have successfully converted human skin cells into fully-functional pancreatic cells. The new cells produced insulin in response to changes in glucose levels, and, when transplanted into mice, the cells protected the animals from developing diabetes in a mouse model of the disease.
Functioning human pancreatic cells after they’ve been transplanted into a mouse are shown. …
Miami Herald Jan 14, 2016 By Glenn Garvin
Keith Oliver, patient 500 to receive a stem-cell transplant for Hodgkin’s lymphoma at the University of Miami’s Sylvester Comprehensive Cancer Center. Oliver was one of many patients celebrating their new lives Thursday, Jan. 14, 2016, at a reunion of stem-cell transplant patients. PEDRO PORTAL pportal@elnuevoherald.com
It wasn’t quite all about the hair when a hundred or so former patients gathered at the Sylvester Comprehensive Cancer Center Thursday
Daily Record Jan 25, 2016 By David Taylor
Multiple sclerosis patient Lucy Clarke is the first Scot to successfully have the radical stem cell treatment that’s being hailed as “miraculous” by experts. Medics are now hopeful that it could eradicate the degenerative neurological condition.
Lucy, from Inverness, had to raise £40,000 for treatment in Moscow as she didn’t qualify for a trial in the UK. But now she’s able to live a more pain-free life …
The Star Jan 19, 2016
Paralysed multiple sclerosis sufferers are walking again thanks to life-changing treatment in Sheffield.
A trial at the Royal Hallamshire Hospital has seen 20 patients receive bone marrow transplants using their own stem cells in a bid to ‘re-boot’ their immune systems, which has helped some people walk again.
The trial is also being run in the US, Sweden and Brazil.
Professor Basil Sharrack, from the Royal Hallamshire Hospital, said: “To …
LA Times Dec 3, 2015 Melissa Healy
An international conference on gene editing on Thursday left the door open to future use, in humans, of new techniques that alter an organism’s genetic architecture in ways that carry forward to future generations.
With questions of safety, need and ethics still unanswered, the U.S. National Academies of Sciences, Engineering and Medicine; the United Kingdom’s Royal Society; and the Chinese Academy of Science agreed that “it would be …
The Lancet Dec 15, 2015 Rebecca Cooney, Editor
Gene editing has swiftly become one of the most promising—and controversial—breakthroughs in genetic engineering.
With the entrance of CRISPR (clustered regularly interspaced short palindromic repeats), a technique using the Cas9 enzyme to cut strands of the genome at precisely targeted locations to insert, replace, or remove DNA, the manipulation of the genetic basis of human disease has once again come to the fore.
Much of the excitement …
MSUnites.com Nov 5, 2015
A new stem cell treatment has sent most of the MS patients who tried it into remission, halting the progression of the disease even several years afterwards.
In a recent clinical study at the COloroda Blood Cancer Institute 24 patients with relapsing remitting multiple sclerosis (RRMS) underwent a three month procedure destroying their immune systems and then had their immune systems restarted using stem cell therapy.
The clinical
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Three years after a small number of patients with multiple sclerosis (MS) were treated with high-dose immunosuppressive therapy (HDIT) and then transplanted with their own hematopoietic stem cells, most of the patients sustained remission of active relapsing-remitting MS (RRMS) and had improvements in neurological function, according to a study published online by JAMA Neurology.
MS is a degenerative disease and most patients with RRMS who received disease-modifying therapies experience breakthrough disease. Autologous (using a patient’s …
Bone marrow is the spongy tissue inside some of the bones in the body, including the hip and thigh bones. Bone marrow contains immature cells, called stem cells.
Numerous people with blood cancers such as leukemia, lymphoma, sickle cell anemia and other life-threatening diseases, rely on bone marrow or cord blood transplants to save their life.
Healthy bone marrow and blood cells are needed in order to live. When disease affects bone marrow so that …
