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CRISPR Gene Editing Can Cause Hundreds of Unintended Mutations

Science Daily May 29, 2017  Columbia University Medical Center As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome. “We feel it’s critical that the scientific community consider the potential hazards of all off-target mutations caused by [...

The Fertility Doctor Trying to Commercialize Three-Parent Babies

Bioethics.com June 26,2017  MIT Technology Review A U.S. fertility doctor has started a company with a provocative vision for older women: become pregnant by having their DNA shifted into a young woman’s egg. The company, Darwin Life, was quietly established last year by John Zhang, also founder of a New York City clinic called New Hope […]

Restoring Sight: CRISPR Could Reprogram Cells to Treat Retinitis pigmentosa

Genetic Literacy Project 4/28/17 University of California San Diego Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of ...

First Human Embryos Edited in the U.S.

Rewriting Life  by Steve Connor  July 26, 2017   A still from a video shows gene-editing chemicals being injected into a human egg at the moment of fertilization. Scientists used the technique to correct DNA errors present in the father’s sperm.OSHU   The first known attempt at creating genetically modified human embryos in the United […]

Turning Skin Cells into Blood Vessel Cells While Keeping Them Young

Science Daily  April 6, 2017 This is a mouse heart section showing human progenitor cells that formed functional human blood vessels. Purple color signifies human blood vessels, red staining signifies the blood vessels of the mouse that received the human cell implants. Credit: Jalees Rehman Researchers from the University of Illinois at Chicago have identified a […]

Firestorm Brewing as Scientists Work to Create Synthetic Human DNA

CNBC  Alex Ossola, special to CNBC.com Tuesday, 2 May 2017   As synthetic DNA is being researched, ethical questions are coming to surface Last May a seemingly commonplace meeting kicked off a firestorm of controversy. More than 100 experts in genetics and bioengineering convened at Harvard Medical School for a meeting that was closed to […]

Unproven Stem Cell ‘Therapy’ Blinds Three Patients at Florida Clinic

Science Daily  March 15, 2017  Stanford University Medical Center Jeffrey Goldberg and his colleagues examined the cases of three women who were blinded after undergoing an unproven stem cell treatment for macular degeneration. Credit: Norbert von der Groeben Three people with macular degeneration were blinded after undergoing an unproven stem cell treatment that was touted […]

Is the 14-day Limit on Growing Embryos Out of Date?

BioEdge April 3, 2017  Michael Cook Both in the US and UK, growing human embryos more than 14 days in a laboratory is banned. Recent developments suggest that it may be possible to grow them for longer and a number of scientists are lobbying to extend the limit. They contend that the limit is out-of-date […]